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Anti-Aging & LongevitySynthetic mitochondria-targeted tetrapeptide
SS-31
$59.99
10 mg· 2 strengths availableSS-31 is a synthetic aromatic-cationic tetrapeptide that associates with cardiolipin, a phospholipid found almost exclusively in the inner mitochondrial membrane.
That selective binding is the reason it is studied: it concentrates in mitochondria and allows researchers to examine how inner-membrane lipid organization influences electron transport efficiency and mitochondrial bioenergetics.
Research areas
Mitochondrial bioenergeticsCardiolipin interactionMembrane biophysicsPreclinical research
Form: Lyophilized (freeze-dried)
- Compound class
- Synthetic mitochondria-targeted tetrapeptide
- Research category
- Anti-Aging & Longevity
- SKU
- NVR-SS-31-10MG
- Alternate name
- Elamipretide
- Appearance
- White lyophilized powder
- Storage
- Store lyophilized at −20 °C. Protect from light and moisture.
Research use only
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Cost per mg shown for each option
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$59.99per 10 mg$6.00/mg
For research use only — not for human or animal consumption.
Supplied solely for legitimate laboratory and research purposes. Not for medical or veterinary use, diagnosis, treatment, or prevention of disease.
Research Grade
Batch Documentation
Research Use Only
U.S.-Based Fulfillment
What you should know
More detail on SS-31.
Analytical values reflect per-lot documentation and appear once a batch is released.
Compound
Cardiolipin organizes respiratory-chain supercomplexes within the inner mitochondrial membrane, and disruption of that organization is associated with reduced electron transport efficiency in published models. SS-31 binds cardiolipin without disrupting the membrane, which makes it a targeted tool for studying that relationship. Laboratory applications include oxygen-consumption and ATP-production assays in isolated mitochondria, reactive-oxygen-species measurement, and preclinical mitochondrial-dysfunction models. Because uptake is driven by lipid affinity rather than a receptor, the peptide behaves differently from conventional ligands and controls should reflect that.
Peptide class
Synthetic mitochondria-targeted tetrapeptide
Mechanism (research context)
SS-31 preferentially associates with the inner mitochondrial membrane, where published research characterizes interaction with cardiolipin and modulation of mitochondrial cristae architecture.
Why it is studied
SS-31 is one of the most extensively cited mitochondria-targeted peptides and is used across cardiac, renal, and neurodegenerative-model research.
Current areas of research
Mitochondrial bioenergeticsCardiolipin interactionMembrane biophysicsPreclinical research
Topics reflect published preclinical and in vitro research. Reference only — not a claim of clinical outcomes.
Scientific background
SS-31 was developed in research at Cornell University as part of a series of mitochondria-targeted (Szeto-Schiller) peptides selected for cationic-aromatic patterning.
It has since become one of the reference compounds in mitochondria-targeted peptide research.
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SS-31
10 mg · $59.99