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MelanocortinSynthetic cyclic heptapeptide (melanocortin analog)

PT-141

$39.99

10 mg

PT-141 (bremelanotide) is a cyclic melanocortin peptide derived from the Melanotan II scaffold, modified to shift its receptor preference toward MC4R.

Because MC4R is expressed predominantly in the central nervous system and is studied in relation to appetite and behavior pathways, this compound is used in preclinical research examining central melanocortin signaling rather than peripheral pigmentation.

Research areas

MC4R receptor signalingCentral melanocortin pathwaysReceptor selectivity studiesPreclinical research

Form: Lyophilized (freeze-dried)

Compound class: Synthetic cyclic heptapeptide (melanocortin analog)
Research category: Melanocortin
SKU: NVR-PT-141-10MG
Alternate name: Bremelanotide
CAS: 189691-06-3
Appearance: White lyophilized powder
Storage: Store lyophilized at −20 °C. Protect from light and moisture.

Research use only

Strength

10 mg$39.99$4.00/mg

$39.99per 10 mg$4.00/mg

For research use only — not for human or animal consumption.

Supplied solely for legitimate laboratory and research purposes. Not for medical or veterinary use, diagnosis, treatment, or prevention of disease.

Research Grade

Batch Documentation

Research Use Only

U.S.-Based Fulfillment

What you should know

More detail on PT-141.

Analytical values reflect per-lot documentation and appear once a batch is released.

Compound

Shifting selectivity within the melanocortin family is chemically difficult because the receptor subtypes share a conserved binding pocket. PT-141 represents a documented case of that shift and is therefore of interest both as a pharmacological tool and as a medicinal-chemistry example. Laboratory applications include MC4R-expressing cell assays measuring cyclic-AMP response, comparative selectivity panels across the receptor family, and preclinical neuroscience models of central melanocortin signaling. Not for human use.

Peptide class

Synthetic cyclic heptapeptide (melanocortin analog)

Mechanism (research context)

PT-141 is characterized as a melanocortin receptor agonist with reported selectivity favoring MC3R/MC4R engagement, used in receptor-pharmacology research.

Why it is studied

It is a defined-sequence reference compound in the melanocortin analog pharmacology literature.

Current areas of research

MC4R receptor signalingCentral melanocortin pathwaysReceptor selectivity studiesPreclinical research

Topics reflect published preclinical and in vitro research. Reference only — not a claim of clinical outcomes.

Scientific background

PT-141 emerged from the Melanotan II series with modifications that shifted its receptor-selectivity profile away from MC1R-dominant activity.

It has since been used as a comparison peptide in melanocortin-selectivity research.

Batch number

Batch documentation will be added when inventory is released.

Purity

≥ 98% (per lot documentation, when available)

Analytical method

RP-HPLC & mass spectrometry (per lot documentation)

Testing laboratory

Independent third-party analytical laboratory

Batch documentation will be added when inventory is released. Once a batch is released, its analytical records and Certificate of Analysis are linked here. Requests: grant@novarynresearch.com.

Research Grade

Batch Documentation Where Available

Laboratory Handling Guidance

Laboratory Use Only

Laboratory concentration calculator

Use the selected research-material amount and your chosen total liquid volume to calculate laboratory concentration.

Material amount

10 mgSelected

From the selected PT-141 strength.

Total liquid volume

Mathematical laboratory concentration calculation only. This tool does not provide preparation recommendations of any kind.

Calculations are a laboratory reference for in vitro work only. No preparation, administration, or human-use guidance is provided.

Storage

Store lyophilized at −20 °C. Protect from light and moisture.

Form

Lyophilized (freeze-dried) powder

Shipping conditions

Ships from the United States in packaging appropriate to the product's storage requirements. Cold-chain packaging is used where required.

Handling recommendations

Handle per institutional laboratory protocols. Wear appropriate PPE, minimize exposure to light and moisture, and record lot information on the working aliquot.

Product name

PT-141

Peptide class

Synthetic cyclic heptapeptide (melanocortin analog)

Research category

Melanocortin

Size

10 mg — $39.99

Appearance

White lyophilized powder

Delivery form

Lyophilized (freeze-dried) powder

CAS number

189691-06-3

Molecular formula

C₅₀H₆₈N₁₄O₁₀

Molecular weight

1025.18 g/mol

Purity specification

≥ 98% (per lot documentation, when available)

Solubility

Soluble in bacteriostatic water

Storage temperature

Store lyophilized at −20 °C. Protect from light and moisture.

Shelf life

24 months lyophilized under recommended storage

Laboratory use

For in vitro research use only. Not for human or veterinary use.

Alternate names

Bremelanotide · PT141

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No — it is derived from MT2 but has a distinct receptor-selectivity profile.

Lyophilized materials are typically reconstituted with bacteriostatic water. Follow institutional protocols and consult the applicable batch documentation when available.

Materials ship in insulated packaging appropriate to their handling requirements. Cold-chain packaging is used where required by the product's storage guidance.

Batch-specific documentation, including a Certificate of Analysis, is provided when available for the released lot. Contact grant@novarynresearch.com for outstanding requests.