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Immune & InflammatoryTripeptide fragment of α-MSH (Lys-Pro-Val)
KPV
$59.99
10 mgKPV is the C-terminal tripeptide fragment (lysine-proline-valine) of alpha-melanocyte-stimulating hormone.
The fragment retains reported anti-inflammatory activity in cell models while lacking the pigmentary activity of the full hormone, which is exactly why it is studied: it separates inflammatory-pathway effects from melanocortin receptor-driven pigmentation in experimental systems.
Research areas
Inflammatory signalingMelanocortin fragment studiesEpithelial cell modelsPreclinical research
Form: Lyophilized (freeze-dried)
- Compound class
- Tripeptide fragment of α-MSH (Lys-Pro-Val)
- Research category
- Immune & Inflammatory
- SKU
- NVR-KPV-10MG
- Alternate name
- Lys-Pro-Val
- CAS
- 67727-97-3
- Appearance
- White lyophilized powder
- Storage
- Store lyophilized at −20 °C. Protect from light and moisture.
Research use only
Strength
10 mg$59.99$6.00/mg
1
$59.99per 10 mg$6.00/mg
For research use only — not for human or animal consumption.
Supplied solely for legitimate laboratory and research purposes. Not for medical or veterinary use, diagnosis, treatment, or prevention of disease.
Research Grade
Batch Documentation
Research Use Only
U.S.-Based Fulfillment
What you should know
More detail on KPV.
Analytical values reflect per-lot documentation and appear once a batch is released.
Compound
Published in vitro work reports that KPV influences NF-κB pathway activity and cytokine expression in cultured epithelial and immune cell lines, and some studies describe uptake through peptide transporters rather than classical melanocortin receptors. That distinction makes the fragment mechanistically interesting in its own right. Laboratory applications include intestinal and dermal epithelial models, inflammatory-signaling assays, and comparative studies against full-length alpha-MSH. All reported findings are preclinical.
Peptide class
Tripeptide fragment of α-MSH (Lys-Pro-Val)
Mechanism (research context)
KPV has been studied in cellular and mucosal-model systems for anti-inflammatory-adjacent signaling attributed to the C-terminal α-MSH fragment.
Why it is studied
KPV is a compact, well-defined tripeptide widely cited in inflammation-research literature as a reference α-MSH fragment.
Current areas of research
Inflammatory signalingMelanocortin fragment studiesEpithelial cell modelsPreclinical research
Topics reflect published preclinical and in vitro research. Reference only — not a claim of clinical outcomes.
Scientific background
The C-terminal tripeptide of α-MSH has been the subject of published research since the 1990s exploring the anti-inflammatory-adjacent activity attributed to α-MSH fragments.
KPV is one of the shortest defined α-MSH-derived research peptides and remains a common reference compound in the literature.
Related
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KPV
10 mg · $59.99