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Anti-Aging & LongevitySynthetic research compound

FOXO4-DRI

$299.99

10 mg

FOXO4-DRI is a D-amino-acid retro-inverso peptide modeled on the FOXO4 transcription factor's p53-interacting region. The retro-inverso design — reversed sequence built from D-amino acids — is intended to resist protease degradation while preserving side-chain presentation.

It is used in laboratory research as a tool for disrupting the FOXO4–p53 interaction in senescent-cell models.

Research areas

Cellular senescence researchFOXO4–p53 interactionPeptide design and stabilityPreclinical research

Form: Lyophilized (freeze-dried)

Compound class: Synthetic research compound
Research category: Anti-Aging & Longevity
SKU: NVR-FOXO4-DRI-10MG
Appearance: Lyophilized powder
Storage: Store lyophilized at −20 °C. Protect from light and moisture.

Research use only

Strength

10 mg$299.99$30.00/mg

$299.99per 10 mg$30.00/mg

For research use only — not for human or animal consumption.

Supplied solely for legitimate laboratory and research purposes. Not for medical or veterinary use, diagnosis, treatment, or prevention of disease.

Research Grade

Batch Documentation

Research Use Only

U.S.-Based Fulfillment

What you should know

More detail on FOXO4-DRI.

Analytical values reflect per-lot documentation and appear once a batch is released.

Compound

Senescent cells resist apoptosis in part through interactions that sequester p53, and FOXO4 has been described as one participant in that arrangement. FOXO4-DRI was designed to interfere with that interaction, making it a widely cited probe in senolytic research. It is also a frequently referenced example of retro-inverso peptide engineering, which is of independent interest to peptide chemists. Laboratory applications include senescent-cell culture models, protein-interaction studies, and comparative work on peptide stability strategies. Findings in this area remain preclinical.

Peptide class

Synthetic research compound

Mechanism (research context)

Extended mechanistic characterization for this compound is available in the published literature. Consult peer-reviewed references for detailed pathway analysis.

Why it is studied

FOXO4-DRI is studied within its research category (Anti-Aging & Longevity) as a defined-sequence reference compound for laboratory investigation.

Current areas of research

Cellular senescence researchFOXO4–p53 interactionPeptide design and stabilityPreclinical research

Topics reflect published preclinical and in vitro research. Reference only — not a claim of clinical outcomes.

Scientific background

FOXO4-DRI is supplied for in vitro laboratory research. Batch-specific analytical documentation is provided when available for the released lot.

Batch number

Batch documentation will be added when inventory is released.

Purity

Batch documentation will be added when inventory is released.

Analytical method

RP-HPLC & mass spectrometry (per lot documentation)

Testing laboratory

Independent third-party analytical laboratory

Batch documentation will be added when inventory is released. Once a batch is released, its analytical records and Certificate of Analysis are linked here. Requests: grant@novarynresearch.com.

Research Grade

Batch Documentation Where Available

Laboratory Handling Guidance

Laboratory Use Only

Laboratory concentration calculator

Use the selected research-material amount and your chosen total liquid volume to calculate laboratory concentration.

Material amount

10 mgSelected

From the selected FOXO4-DRI strength.

Total liquid volume

Mathematical laboratory concentration calculation only. This tool does not provide preparation recommendations of any kind.

Calculations are a laboratory reference for in vitro work only. No preparation, administration, or human-use guidance is provided.

Storage

Store lyophilized at −20 °C. Protect from light and moisture.

Form

Lyophilized (freeze-dried) powder

Shipping conditions

Ships from the United States in packaging appropriate to the product's storage requirements. Cold-chain packaging is used where required.

Handling recommendations

Handle per institutional laboratory protocols. Wear appropriate PPE, minimize exposure to light and moisture, and record lot information on the working aliquot.

Product name

FOXO4-DRI

Peptide class

Synthetic research compound

Research category

Anti-Aging & Longevity

Size

10 mg — $299.99

Appearance

Lyophilized powder

Delivery form

Lyophilized (freeze-dried) powder

CAS number

Batch documentation will be added when inventory is released.

Molecular formula

Batch documentation will be added when inventory is released.

Molecular weight

Batch documentation will be added when inventory is released.

Purity specification

≥ 98% (per lot documentation, when available)

Solubility

Batch documentation will be added when inventory is released.

Storage temperature

Store lyophilized at −20 °C. Protect from light and moisture.

Shelf life

24 months lyophilized under recommended storage

Laboratory use

For in vitro research use only. Not for human or veterinary use.

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Batch-specific documentation, including a Certificate of Analysis, is provided when available for the released lot. Contact grant@novarynresearch.com for outstanding requests.

Follow institutional protocols for the handling of research-use lyophilized materials.

Lyophilized materials are typically reconstituted with bacteriostatic water. Follow institutional protocols and consult the applicable batch documentation when available.

Materials ship in insulated packaging appropriate to their handling requirements. Cold-chain packaging is used where required by the product's storage guidance.