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Growth Hormone ResearchSynthetic pentapeptide (selective ghrelin-receptor agonist)

Ipamorelin

$39.99

5 mg· 2 strengths available

Ipamorelin is a synthetic pentapeptide that acts as an agonist at the growth hormone secretagogue receptor (GHS-R1a), the same receptor engaged by the endogenous peptide ghrelin.

It is widely used in laboratory research because published characterization describes it as more selective than earlier secretagogue peptides, which makes it useful for isolating GHS-R1a-mediated signaling from other endocrine effects in preclinical models.

Research areas

Ghrelin receptor activityReceptor selectivity studiesSomatotroph pathway researchPreclinical research

Form: Lyophilized (freeze-dried)

Compound class: Synthetic pentapeptide (selective ghrelin-receptor agonist)
Research category: Growth Hormone Research
SKU: NVR-IPAMORELIN-5MG
Alternate name: Ipa
CAS: 170851-70-4
Appearance: White lyophilized powder
Storage: Store lyophilized at −20 °C. Protect from light and moisture.

Research use only

Select strength

Cost per mg shown for each option

$39.99per 5 mg$8.00/mg

For research use only — not for human or animal consumption.

Supplied solely for legitimate laboratory and research purposes. Not for medical or veterinary use, diagnosis, treatment, or prevention of disease.

Research Grade

Batch Documentation

Research Use Only

U.S.-Based Fulfillment

What you should know

More detail on Ipamorelin.

Analytical values reflect per-lot documentation and appear once a batch is released.

Compound

GHS-R1a is a G-protein-coupled receptor that signals largely through the Gq/phospholipase-C pathway, producing measurable calcium mobilization in receptor assays. Ipamorelin's short, defined sequence and reported selectivity profile make it a common reference agonist in that setting. Investigators use it to compare secretagogue potency, to examine receptor desensitization over repeated stimulation, and as a positive control when characterizing novel GHS-R1a ligands. Its use here is limited to in vitro and preclinical laboratory research.

Peptide class

Synthetic pentapeptide (selective ghrelin-receptor agonist)

Mechanism (research context)

Ipamorelin engages GHSR-1a with reported selectivity relative to earlier GHRP-family peptides, which is why it is commonly used as a receptor-pharmacology reference compound.

Why it is studied

Its selectivity profile makes it a widely cited comparison peptide in ghrelin-receptor and secretagogue pharmacology.

Current areas of research

Ghrelin receptor activityReceptor selectivity studiesSomatotroph pathway researchPreclinical research

Topics reflect published preclinical and in vitro research. Reference only — not a claim of clinical outcomes.

Scientific background

Ipamorelin was described in the late 1990s as one of the first selective growth hormone secretagogues, distinguishing it from broader-acting members of the GHRP series.

It is now a standard reference peptide in ghrelin-receptor research and is commonly paired with GHRH analogs such as CJC-1295 in co-treatment protocols.

Batch number

Batch documentation will be added when inventory is released.

Purity

≥ 98% (per lot documentation, when available)

Analytical method

RP-HPLC & mass spectrometry (per lot documentation)

Testing laboratory

Independent third-party analytical laboratory

Batch documentation will be added when inventory is released. Once a batch is released, its analytical records and Certificate of Analysis are linked here. Requests: grant@novarynresearch.com.

Research Grade

Batch Documentation Where Available

Laboratory Handling Guidance

Laboratory Use Only

Laboratory concentration calculator

Use the selected research-material amount and your chosen total liquid volume to calculate laboratory concentration.

Material amount

5 mgSelected

From the selected Ipamorelin strength.

Total liquid volume

Mathematical laboratory concentration calculation only. This tool does not provide preparation recommendations of any kind.

Calculations are a laboratory reference for in vitro work only. No preparation, administration, or human-use guidance is provided.

Storage

Store lyophilized at −20 °C. Protect from light and moisture.

Form

Lyophilized (freeze-dried) powder

Shipping conditions

Ships from the United States in packaging appropriate to the product's storage requirements. Cold-chain packaging is used where required.

Handling recommendations

Handle per institutional laboratory protocols. Wear appropriate PPE, minimize exposure to light and moisture, and record lot information on the working aliquot.

Product name

Ipamorelin

Peptide class

Synthetic pentapeptide (selective ghrelin-receptor agonist)

Research category

Growth Hormone Research

Available sizes

5 mg — $39.99 10 mg — $49.99

Appearance

White lyophilized powder

Delivery form

Lyophilized (freeze-dried) powder

CAS number

170851-70-4

Molecular formula

C₃₈H₄₉N₉O₅

Molecular weight

711.86 g/mol

Purity specification

≥ 98% (per lot documentation, when available)

Solubility

Soluble in bacteriostatic water

Storage temperature

Store lyophilized at −20 °C. Protect from light and moisture.

Shelf life

24 months lyophilized under recommended storage

Laboratory use

For in vitro research use only. Not for human or veterinary use.

Alternate names

Ipa

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Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (with non-standard residues at positions 1 and 3).

Lyophilized materials are typically reconstituted with bacteriostatic water. Follow institutional protocols and consult the applicable batch documentation when available.

Materials ship in insulated packaging appropriate to their handling requirements. Cold-chain packaging is used where required by the product's storage guidance.

Batch-specific documentation, including a Certificate of Analysis, is provided when available for the released lot. Contact grant@novarynresearch.com for outstanding requests.