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Cognitive / NeuroSmall peptide-mimetic (angiotensin IV analog)
Dihexa
$79.99
10 mgDihexa is a small-molecule derivative of angiotensin IV, modified with hexanoic acid groups to improve stability and membrane permeability.
Its research interest centers on reported potentiation of hepatocyte growth factor signaling through the c-Met receptor, a pathway studied in neuronal culture models for its role in synapse formation and dendritic architecture.
Research areas
HGF/c-Met signalingSynaptogenesis researchAngiotensin IV derivativesPreclinical research
Form: Lyophilized (freeze-dried)
- Compound class
- Small peptide-mimetic (angiotensin IV analog)
- Research category
- Cognitive / Neuro
- SKU
- NVR-DIHEXA-10MG
- Alternate name
- N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
- Appearance
- White to off-white lyophilized powder
- Storage
- Store lyophilized at −20 °C. Protect from light and moisture.
Research use only
Strength
10 mg$79.99$8.00/mg
1
$79.99per 10 mg$8.00/mg
For research use only — not for human or animal consumption.
Supplied solely for legitimate laboratory and research purposes. Not for medical or veterinary use, diagnosis, treatment, or prevention of disease.
Research Grade
Batch Documentation
Research Use Only
U.S.-Based Fulfillment
What you should know
More detail on Dihexa.
Analytical values reflect per-lot documentation and appear once a batch is released.
Compound
The angiotensin IV system has been investigated for central nervous system effects distinct from classical blood-pressure regulation, and Dihexa emerged from efforts to make that chemistry more stable and brain-penetrant in preclinical models. Published work describes it as an allosteric potentiator of HGF at c-Met rather than a direct agonist, which is a mechanistically specific claim worth verifying with appropriate controls. Laboratory applications include neuronal culture assays measuring dendritic spine density, receptor-signaling studies, and preclinical cognition models.
Peptide class
Small peptide-mimetic (angiotensin IV analog)
Mechanism (research context)
Published research characterizes dihexa as a HGF/c-Met pathway modulator in cellular systems, with reported activity in synaptogenesis models.
Why it is studied
Dihexa is a widely referenced research probe in the angiotensin IV analog literature and neurotrophic-pathway modeling.
Current areas of research
HGF/c-Met signalingSynaptogenesis researchAngiotensin IV derivativesPreclinical research
Topics reflect published preclinical and in vitro research. Reference only — not a claim of clinical outcomes.
Scientific background
The angiotensin IV analog series was developed at Washington State University in research on neurotrophic peptide-mimetics.
Dihexa emerged from that program as a compact analog with reported in-vitro activity in neuronal-culture models. It is used as a research probe for the associated signaling pathways.
Related
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Dihexa
10 mg · $79.99